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16.1: Relationship between efficacy and toxicity oftheophylline with its plasma concentration. When FTD is associated withMND, patients may have strong, uncontrollable burstsof laughing or crying, referred to as pseudobulbar affect(PBA) (Chang et al., 2005), and symptoms of PBA in thesetting of FTD should prompt investigations for MND.The behavioral symptoms in FTD-MND are similar tothose occurring in FTD without MND, although psy-chotic symptoms are more common in FTD-MND (Lilloet al., 2010).
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Vit B12and folic acid are therefore called maturationfactors. Some of the triazine herbicides have beenranked by USEPA’s Office of Pesticide Program: (i) atra-zine: Not Likely to be Carcinogenic to Humans; (ii) propa-zine: Not Likely to be Carcinogenic to Humans; and(iii) simazine: Not Likely to be Carcinogenic to Humans.While atrazine has been reported to cause mammary tumorsin Sprague–dawley rats buy topamax in bulk a fairly recent review and riskassessment concluded that this lone finding has no relevancefor humans (i.e., the finding in female Sprague–dawley ratsis a strain-, sex-, and tissue-specific effect). Unfortunately buy topamax in bulk these changes only appearwhen the majority (>50–75%) of the bone matrix is lost, which typically takes at least 2weeks .
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