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However, the concentra-tions of the chemicals detected in human samples are gen-erally very low, typically in the parts per billion (ppb) orparts per trillion (ppt) range, and the degree of risk posedby these chemicals depends on whether the exposure levelsapproach those known to cause toxicity in test animals orpeople. (2004) Effects of immediateversus delayed antihypertensive therapy on outcome in the Sys-tolic Hypertension in Europe Trial. Bothhave the potential for serious adverse conse-quences, and therefore care should be taken inassessing the need for intervention, taking intoaccount the child’s age, condition, and thepresence of contraindications or precautions.The modalities used should be carefullyselected and applied in order to minimise orprevent complications. 11.27 Pressure–volume (PV) loop during mechanicalventilation with an extrinsic PEEP of 8 cm H2O.

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