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AIDS), infections bylow grade pathogens and intracellular organismsabound. The majority ofthese are located in the DNA binding domain (DBD) and con?ned to small con-served regions [ 46 , 56]

The majority ofthese are located in the DNA binding domain (DBD) and con?ned to small con-served regions [ 46 , 56]. Inthe Zurich classification, it labels a heterogenous group of chronic inflammatory bonediseases, mostly of unknown etiology. Each chainhas a short amino-terminus domain (7S domain), a longmiddle collagenous helical domain (which interacts withthe remaining two chains in the fully assembled molecule),and a carboxy-terminus globular noncollagenousdomain (NC1 domain).

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12.2).In general, the contents of the perinuclear cytoplasm of thecell body and cytoplasm of dendrites are similar, with theexception ofthe Golgi apparatus. The new bone appears eosinophilic in contrast to the morebasophilic appearance of the surrounding cartilage (C)

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